At Linköping University, she leads research initiatives in AI-assisted saliva diagnostics, tissue regeneration, personalised periodontal treatment, and register-based clinical studies in collaboration with regional partners and national quality registries. Her work is highly interdisciplinary and aims to deliver clinically meaningful solutions that advance prevention, early diagnosis, and patient-centred care.
Shariel Sayardoust
Adjunct Associate Professor, Docent
Shariel Sayardoust is a specialist in periodontology, Head of Research, and Associate Professor with a strong focus on the interplay between oral and systemic health.
Research
Funded projects
Automated Registration and Follow-up of Dental Implants using QR Code Scanning (SKRI)
The project aims to develop and implement an automated system for registration and follow-up of dental implants using QR code scanning. The solution will ensure traceability, streamline data entry, and enable standardized documentation. The goal is to improve quality monitoring, facilitate research, and create a foundation for AI-based analyses in dental care.
Read more about the project .
Publications
2025
2024
2023
Earlier Publications
Original works
- Sayardoust S, Ekstrom J. Parasympathetic nerve-evoked protein synthesis, mitotic activity and salivary secretion in the rat parotid gland and the dependence on NO-generation. Archives of Oral Biology, 2003, 51(3), 189-197.
- Sayardoust S, Ekstrom J. Nitric oxide-dependent in vitro secretion of amylase from innervated or chronically denervated parotid glands of the rat in response to isoprenaline and vasoactive intestinal peptide. Experimental Physiology. 2003 May;88(3):381-387.
- Sayardoust S, Ekstrom J. Nitric oxide-dependent protein synthesis in parotid and submandibular glands of anaesthetized rats upon sympathetic stimulation or isoprenaline administration. Experimental Physiology. 2004 Mar;89(2):219-227
- Ekstrom J, Cevik H, Sayardoust S. Nitric oxide-dependent mitotic activity in salivary glands of the rat upon sympathetic stimulation. Archives of Oral Biology. 2004 Nov;49(11):889-894.
- Ekstrom J, Cevik H, Sayardoust S. Neural- and Hormonal-induced Protein Synthesis and Mitotic Activity in the Rat Parotid Gland and the Dependence on NO-generation. Journal of Oral Biosciences. 2007;49(1):31-38.
- Sayardoust S, Gr枚ndahl K, Johansson E, Thomsen P, Slotte C. Implant Survival and Marginal Bone Loss at Turned and Oxidized Implants in Periodontitis-Susceptible Smokers and Never-Smokers: A Retrospective, Clinical, Radiographic Case-Control Study. Journal of Periodontology. 2013 Dec;84(12):1775-1782.
- Sayardoust S, Omar O, Thomsen P, Norderyd O. Gene expression in peri-implant crevicular fluid of smokers and non-smokers. 1. The early phase of osseointegration. Clinical Implant Dentistry and Related Research. 2017 Aug;19(4):681-693
- Sayardoust S, Omar O, Thomsen P, Norderyd O. Clinical, radiological and gene expression analyses in smoker and non-smokers. 2. The late healing phase of osseointegration. Clinical Implant Dentistry and Related Research. 2017 Jul 26
- Sayardoust S, Omar O, Thomsen P. Implant-associated gene expression in the jaw bone of smokers and nonsmokers: A human study using quantitative qPCR. Clinical Oral Implants Research. 2018 Aug 30. doi: 10.1111/clr.13351,
- Andersson B脜, Sayardoust S, L枚fgren S, Rutqvist LE, Laytragoon-Lewin N. Cigarette smoking affects microRNAs and inflammatory biomarkers in healthy individuals and an association to single nucleotide polymorphisms is indicated. Biomarkers. 2018 Oct 30:1-17.
- Sayardoust S, Shah FA*, Thomsen P, Palmquist A. Extracellular matrix composition during bone regeneration in the human dental alveolar socket. Bone. 2019 Oct;127:244-249. doi: 10.1016/j.bone.2019.06.003. Epub 2019 Jun 6.
- Sayardoust S, Shah FA*, Thomsen P, Palmquist A. Does Smoking Impair Bone Regeneration in the Dental Alveolar Socket? Calcified Tissue International. 2019 Dec;105(6):619-629. doi: 10.1007/s00223-019-00610-4. Epub 2019 Sep 18.
- Laytragoon Lewin N, Karlsson JE, Robinsson D, Fagerberg M, Kentsson M, Sayardoust S, Nilsson M, Shamoun L, Andersson B脜, L枚fgren S, Rutqvist LE, Lewin F. Influence of single nucleotide polymorphisms among cigarette smoking and non-smoking patients with coronary artery disease, urinary bladder cancer and lung cancer. PLoS One. 2021 Jan 28;16(1) doi: 10.1371/journal.pone.0243084.
- Sayardoust S, Norstedt W, & Shah FA. The long鈥恡erm impact of alveolar ridge preservation with xenograft bone mineral on peri鈥恑mplant health after 5 years in function: A retrospective cohort study of 108 patients assessed clinically and radiologically. Clinical and Experimental Dental Research.
- Kvarnvik C, Ahonen, Jansson H, Brostr枚m A, Stensson M, Sayardoust S. Clinical and radiographic periodontal status in hypertensive patients with or without obstructive sleep apnea 10 years after diagnosis and CPAP initiation. Clinical and Experimental Dental Research. 2024 Apr;10(2) doi: 10.1002/cre2.859.
- Sayardoust S, Johansson A, J枚nsson D. Do Probiotics Cause a Shift in the Microbiota of Dental Implants - A Systematic Review and Meta-Analysis. Frontiers in Cellular and Infection Microbiology. 2022 Mar 16;12:823985. doi: 10.3389/fcimb.2022.823985.
Review Articles/Consensus Reports
- Schwarz F, Alcoforado G, Guerrero A, J枚nsson D, Klinge B, Lang N, Mattheos N, Mertens B, Pitta J, Ramanauskaite A, Sayardoust S, Sanz-Martin I, Stavropoulos A, Heitz-Mayfield L. Peri-implantitis: Summary and consensus statements of group 3. The 6th EAO Consensus Conference 2021. Clinical Oral Implants Research. 2021 Oct;32 Suppl 21:245-253. doi: 10.1111/clr.13827. Impact Factor: 5.02, Kvartil: Q1, Citations: 77
CV
Current Roles
- Head of Research, Public Dental Service (USVE), Region Östergötland
- Associate Professor and Researcher, Linköping University
- President, Swedish Society of Periodontology
- WCMM-associated fellow (AI-based saliva diagnostics)
Research Areas
- Periodontitis and systemic diseases, including dementia, rheumatoid arthritis, obstructive sleep apnoea, and cardiometabolic conditions
- AI-based saliva diagnostics and biohybrid sensor platforms
- Regenerative periodontal treatment and clinical trials (e.g., Emdogain/flapless techniques)
- Register-based research (SKaPa, RRCT, SKRI)
- Early diagnostics, personalised treatment strategies, and implementation of evidence-based care
Teaching and Supervision
- Course director and examiner for Public Dental Health (Linköping University)
- Supervisor for PhD students, specialist trainees, and research-preparatory programmes
- Actively involved in developing the research and education structure within the USVE framework
Collaboration and Leadership
- Leads interdisciplinary research projects in collaboration with universities, healthcare regions and national organisations
- Responsible for establishing a dental research platform with focus on AI, medtech, regeneration, and register-based studies
- Project leader for the development of SKRI and several multicentre clinical studies