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Photo of Wen Zhong

Wen Zhong

Assistant Professor, Docent

My research mainly focuses on the integration of multi-omics, the interplay between genetics and phenotypes, and the development of data-driven strategies/tools for precision medicine.

Research Interests:

My research mainly focuses on the integration of multi-omics, the interplay between genetics and phenotypes, and the development of data-driven strategies/tools for precision medicine. The aim is to investigate the molecular biomarkers for the estimation of disease risks, early diagnosis of disease, stratification of drug treatment response, disease progression monitoring and the stratification of patients.

Publications

2025

Ziyang Tan, Wen Zhong, Hanna Danielsson, Aron Arzoomand, Tadepally Lakshmikanth, Qi Chen, Jaromir Mikes, Jun Wang, Yang Chen, Anna James, Anders K. Nilsson, Anders Elfvin, Nele Brusselaers, Theo Portlock, Pia Lundgren, Karin Savman, Dirk Wackernagel, Ingrid Hansen-Pupp, David Ley, Mathias Uhlen, Ann Hellstrom, Petter Brodin (2025) iScience, Vol. 28, Article 112918 (Article in journal)
Jing Wang, Alberto Zenere, Xingyue Wang, Goeran Bergstrom, Fredrik Edfors, Mathias Uhlen, Wen Zhong (2025) Genome Medicine, Vol. 17, Article 68 (Article in journal)
Mengnan Shi, Loren Mear, Max Karlsson, Maria Bueno Alvez, Andreas Digre, Rutger Schutten, Borbala Katona, Jimmy Vuu, Emil Lindstrom, Feria Hikmet, Han Jin, Meng Yuan, Xiangyu Li, Hong Yang, Xiya Song, Evelina Sjostedt, Fredrik Edfors, Per Oksvold, Kalle von Feilitzen, Martin Zwahlen, Mattias Forsberg, Fredric Johansson, Jan Mulder, Tomas Hokfelt, Yonglun Luo, Lynn Butler, Wen Zhong, Adil Mardinoglu, Asa Sivertsson, Fredrik Ponten, Linn Fagerberg, Cecilia Lindskog, Mathias Uhlen, Cheng Zhang (2025) Genome Biology, Vol. 26, Article 152 (Article in journal)
Sallam Abdallah, Mouna Tabebi, Sawsan Qanadilo, Neserin Ali, Jing Wang, Padraig D´arcy, Wen Zhong, Folke Sjöberg, Moustafa Elmasry, Ahmed Elserafy (2025) Scientific Reports, Vol. 15, Article 3629 (Article in journal)

2024

Tomas Hokfelt, Swapnali Barde, Wen Zhong, Zhi-Qing David Xu, Peteris Alberts (2024) Proceedings of the Estonian Academy of Sciences, Vol. 73, p. 170-192 (Article in journal)

Selected publications

See full list in Google Scholar:

  1. Zhong W, Barde S, Mitsios N, Adori C, Oksvold P, Feilitzen K.V, O’Leary L, Csiba L, Hortobágyi T, Szocsics P and Mechawar N, Maglóczky Z, Renner E, Palkovits M, Uhlen M, Mulder J, Hökfelt T. (2022). The neuropeptide landscape of human prefrontal cortex. Proceedings of the National Academy of Sciences, 119(33), p.e2123146119.
  2. Zhong W, Altay O, Arif M, Edfors F, Mardinoglu A, Uhlén M, Fagerberg L. (2021). Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms. EBioMedicine 74, 103723
  3. Zhong W, Edfors F, Gummesson A, Bergstrom G, Fagerberg L, Uhlén M. (2021). Next generation plasma proteome profiling to monitor health and disease. Nature communications 12 (1), 1-12
  4. Karlsson MJ, Zhang C, Méar L, Zhong W, Digre A, Katona B, Sjöstedt E, Butler L, Odeberg J, Dusart P, Edfors F, Oksvold P, von Feilitzon K, Zwahlen M, Muhammad A, Altay O, Li X, Ozcan M, Mardonoglu A, Fagerberg L, Mulder J, Luo Y, Ponten F, Uhlen M, Lindskog C. (2021). A single–cell type transcriptomics map of human tissues. Science Advances, 7(31), p.eabh2169.
  5. Zhong W, Danielsson H, Tebani A, Karlsson MJ, Elfvin A., Hellgren, G., Brusselaers, N., Brodin, P., Hellström, A., Fagerberg, L., Uhlén, M., (2021). Dramatic changes in blood protein levels during the first week of life in extremely preterm infants. Pediatric research, 89(3), pp.604-612.
  6. Zhong W, Gummesson A, Tebani A, Karlsson M J, Hong MG, Schwenk JM, Edfors F, Bergström G, Fagerberg L, Uhlén M. (2020). Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort. Genome Medicine, 12(1), 1-16.
  7. Tebani A, Gummesson A, Zhong W, Koistinen IS, Lakshmikanth T, Olsson LM, Boulund F, Neiman M, Stenlund H, Hellström C, Karlsson MJ, Arif M, Dodig-Crnković T, Mardinoglu A, Lee S, Zhang C, Chen Y, Olin A, Mikes J, Danielsson H, von Feilitzen K, Jansson PA, Angerås O, Huss M, Kjellqvist S, Odeberg J, Edfors F, Tremaroli V, Forsström B, Schwenk JM, Nilsson P, Moritz T, Bäckhed F, Engstrand L, Brodin P, Bergström G, Uhlén M, Fagerberg L. (2020). Integration of molecular profiles in a longitudinal wellness profiling cohort. Nature communications, 11(1), 1-14.
  8. Sjöstedt E, Zhong W, Fagerberg L, Karlsson M, Mitsios N, Adori C, Oksvold P, Edfors F, Limiszewska A, Hikmet F, Huang J, Du Y, Lin L, Dong Z, Yang L, Liu X, Jiang H, Xu X, Wang J, Yang H, Bolund L, Mardinoglu A, Zhang C, von Feilitzen K, Lindskog C, Pontén F, Luo Y, Hökfelt T, Uhlén M, Mulder J. (2020). An atlas of the protein-coding genes in the human, pig, and mouse brain. Science, 367 (6482)
  9. Uhlén M, Karlsson MJ, Zhong W, Tebani A, Pou C, Mikes J, Lakshmikanth T, Forsström B, Edfors F, Odeberg J, Mardinoglu A, Zhang C, von Feilitzen K, Mulder J, Sjöstedt E, Hober A, Oksvold P, Zwahlen M, Ponten F, Lindskog C, Sivertsson Å, Fagerberg L, Brodin P. (2019). A genome-wide transcriptomic analysis of protein-coding genes in human blood cells. Science, 366 (6472)
  10. Hou J#, Li Z#, Zhong W#, Hao Q, Lei L, Wang L, Zhao D, Xu P, Zhou Y, Wang Y, Xu T. (2017). Temporal transcriptomic and proteomic landscapes of deteriorating pancreatic islets in type 2 diabetic rats. Diabetes, 66(8), 2188-2200 (# equal contribution)

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