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Emergency Medicine Research Center (EMRC)

Video that gives an insight into the operations in the emergency clinic at the University Hospital in Linköping.

The research and development unit of the Emergency Department at ¸£Àû¼§ Hospital was started in 2016. In 2021, the Emergency Department became Sweden's first university healthcare unit in emergency medicine.

We conduct clinical and translational research to improve care for the nearly two million patients who require emergency medical care in Sweden each year. Our research group, part of Sweden's first emergency physician–led emergency department, pursues research spanning the full breadth of emergency medicine — from mechanistic basic science in microcirculation and imaging technology, through clinical trials of diagnostics, assessment and treatment methods, medical devices, and pharmaceuticals, to data-driven prediction methods and research encompassing patient experiences and the psychological dimensions of acute illness. The group currently comprises approximately 20 members, primarily physicians and nurses, but also biologists, engineers, and programmers, as well as visiting researchers. We maintain an active doctoral education program in emergency medicine, and several of our doctoral students hold their primary employment in other health care regions.

Collaborate with us

We receive numerous inquiries regarding study visits, collaborations, and opportunities for degree projects, doctoral education, or other forms of joint work. We welcome all such inquiries. To manage the high volume of requests, we direct inquiries to the contact channels listed below. We process incoming requests on an ongoing basis and can typically respond within two weeks.

Collaboration

We prioritize research collaborations related to projects within our areas of focus, particularly those with clear synergies for both parties.

Note: Purely commercial inquiries — for example, concerning contract research — should be directed through Region Östergötland's official channels and are not handled by individual investigators.

Degree Projects and Student Work

We have extensive experience supervising students in degree projects at both the undergraduate and graduate levels. To maintain the quality of supervision, the number of students we can accept each term is limited; applicants should therefore submit their requests well in advance. We generally prioritize projects aligned with our areas of focus, but we also welcome concrete proposals outside those areas, provided the applicant can articulate a compelling rationale.

Doctoral Education

Our group currently includes approximately ten doctoral students, and we host one to two thesis defenses per year. Several of our doctoral students hold their primary appointments outside Linköping University and Region Östergötland — in other regions as well as in the private sector. We have considerable experience with remote supervision and regard it as a central mission to enable high-quality doctoral education even in settings where clinical emergency medicine is still developing. In general, this requires that the applicant holds a position as a resident physician, specialist physician, or advanced-practice nurse and has an employer willing to support participation in a doctoral program. We are happy to answer questions and to inform prospective students and their employers about the available opportunities.

Visiting Researchers and Postdoctoral Fellows

We maintain several international collaborations and can host visiting researchers at the postdoctoral level or above. Investigators who hold a doctoral degree and are interested in collaboration are encouraged to contact: daniel.wilhelms@liu.se

Examination and Review Assignments

For requests involving thesis committee membership, external examination (opponent), mid-term review, or evaluation of academic appointments, we recommend direct contact with the relevant researcher. Alternatively, inquiries may be directed to our subject representative, who can assist in identifying suitable candidates. The community of emergency medicine researchers in Sweden remains relatively small, and we prioritize providing expert review when needed.

Study Visits

We receive numerous requests for study visits — both to our clinical operations and to our research laboratory. We accept nearly all such requests, as we consider visits a valuable opportunity. However, we generally require several months' notice to arrange visits appropriately. Prospective visitors should consider what topics they wish to learn more about and contact us well in advance. For inquiries, please contact: joakim.henricson@liu.se

News

Publications

Selected publications

  1. M. Jörg, M. Öster, J. Wretborn, D.B. Wilhelms, . Intensive Care Medicine Experimental, volume 11, Article number: 80 (2023)
  2. Hörlin, E., S. Munir Ehrlington, J. Henricson, R.T. John and D. Wilhelms, . BMC Emergency Medicine, 2023. 23, Article number: 124 (2023)
  3. Wretborn, J., M. Jörg, P. Benjaminsson Nyberg and D.B. Wilhelms, . Scientific Reports, 2023. 13(1): p. 5469.
  4. Ardsby, M., F. Shayo, F.M. Sakita, D. Wilhelms, B. Moshi, P. Frankiewicz, L.L. Silva, C.A. Staton, B. Mmbaga and A. Joiner, . BMJ Open, 2023. 13(2): p. e068484.
  5. Wretborn, J., U. Ekelund and D. B. Wilhelms, . Journal of the American College of Emergency Physicians Open, 2022. 3(1): p. e12648.
  6. Wilhelms, S.B. and D.B. Wilhelms, . BMC Emergency Medicine, 2022. 22(1): p. 67.
  7. Hörlin, E., S. Munir Ehrlington, J. Henricson, R.T. John and D. Wilhelms, . Academic Emergency Medicine, 2022. 29(12): p. 1431-1437.
  8. Henricson, J., F. Sjoberg, F. Iredahl, T. Stromberg and D. Wilhelms, . Sci Rep, 2022. 12(1): p. 6594.
  9. Henricson, J., U. Ekelund, J. Hartman, B. Ziegler, L. Kurland and D. Björk Wilhelms, . BMC Emergency Medicine, 2022. 22(1): p. 58.
  10. Davidson, L.T., E. Gauffin, P. Henanger, M. Wajda, D. Wilhelms, B. Ekman, H. Arnqvist, M. Schilling and I.S. Chisalita, . Upsala Journal of Medical Sciences, 2022. 127(1).
  11. Crilly, J., Y.L. Huang, M. Krahe, D. Wilhelms, U. Ekelund, E. Hörlin, J. Hayes and G. Keijzers, . Journal of the American college of emergency physicians open, 2022. 3(6): p. e12852.
  12. Wretborn, J., H. Starkenberg, T. Ruge, D.B. Wilhelms and U. Ekelund, . BMC Emergency Medicine, 2021. 21(1): p. 21.
  13. Wretborn, J., M. Jörg, P. Benjaminsson Nyberg and D.B. Wilhelms, . Journal of the American College of Emergency Physicians open, 2021. 2(5): p. e12530.
  14. Wilhelms, S.B. and D.B. Wilhelms, . BMC emergency medicine, 2021. 21(1): p. 1-9.
  15. Holmbom, M., M. Andersson, S. Berg, D. Eklund, P. Sobczynski, D. Wilhelms, A. Moberg, M. Fredrikson, Å.Ö. Balkhed and H. Hanberger, . BMJ open, 2021. 11(11): p. e052582.
  16. Henricson, J., J. Glasin, S. Rindebratt and D. Wilhelms, . Journal of Biophotonics, 2021: p. e202100270.
  17. Wretborn, J., J. Henricson, U. Ekelund and D.B. Wilhelms, . BMC Emergency Medicine, 2020. 20(1): p. 50.
  18. Greenslade, J.H., M. Wallis, A.N.B. Johnston, E. Carlstrom, D.B. Wilhelms and J. Crilly, . Emerg Med J, 2020. 37(2): p. 106-111.
  19. Brito, H.O., D. Radulski, D.B. Wilhelms, A. Stojakovic, L.M.O. Brito, R.M. Gil da Costa, E. Trindade, D. Engblom, C.R.C. Franco and A.R. Zampronio, . Scientific Reports, 2020. 10(1): p. 4073.
  20. Wretborn, J., U. Ekelund and D.B. Wilhelms, . Front Public Health, 2019. 7(267): p. 267.
  21. Toll John, R., J. Henricson, C.D. Anderson and D. Bjork Wilhelms, . Emerg Med J, 2019. 36(8): p. 465-471.
  22. Greenslade, J.H., M.C. Wallis, A. Johnston, E. Carlström, D. Wilhelms, O. Thom, L. Abraham and J. Crilly, . BMJ Open, 2019. 9(12): p. e033053.
  23. Glasin, J., J. Henricson, L.G. Lindberg and D. Wilhelms, . J Biophotonics, 2019. 12(4): p. e201800275.
  24. Fagerstrom, J., M. Bang, D. Wilhelms and M.S. Chew, . Sci Rep, 2019. 9(1): p. 15132.
  25. Wilhelms, D.B., H. Dock, H.O. Brito, E. Pettersson, A. Stojakovic, J. Zajdel, D. Engblom, E. Theodorsson, M.L. Hammar and A.E. Spetz Holm, . Front Pharmacol, 2018. 9(1452): p. 1452.
  26. Wilhelms, D., F. Sjoberg and M. Chew, . Eur J Anaesthesiol, 2018. 35(3): p. 231-232.
  27. Klawonn, A.M., D.B. Wilhelms, S.H. Lindstrom, A.K. Singh, M. Jaarola, J. Wess, M. Fritz and D. Engblom, . Front Mol Neurosci, 2018. 11: p. 139.
  28. John, R.T., J. Henricson, G.E. Nilsson, D. Wilhelms and C.D. Anderson, . J Biophotonics, 2018. 11(1).
  29. John, R.T., J. Henricson, J. Junker, C.O. Jonson, G.E. Nilsson, D. Wilhelms and C.D. Anderson, . J Biophotonics, 2018. 11(6): p. e201700371.
  30. Nilsson, A., D.B. Wilhelms, E. Mirrasekhian, M. Jaarola, A. Blomqvist and D. Engblom, . Brain Behav Immun, 2017. 61: p. 236-243.
  31. Henricson, J., R. Toll John, C.D. Anderson and D. Bjork Wilhelms, . J Vis Exp, 2017(130).
  32. Fritz, M., A.M. Klawonn, A. Nilsson, A.K. Singh, J. Zajdel, D.B. Wilhelms, M. Lazarus, A. Lofberg, M. Jaarola, U.O. Kugelberg, T.R. Billiar, D.J. Hackam, C.P. Sodhi, M.D. Breyer, J. Jakobsson, M. Schwaninger, G. Schutz, J.R. Parkitna, C.B. Saper, A. Blomqvist, and D. Engblom, . J Clin Invest, 2016. 126(2): p. 695-705.
  33. Brito, H.O., D.R. Radulski, D.B. Wilhelms, A. Stojakovic, L.M. Brito, D. Engblom, C.R. Franco and A.R. Zampronio, . J Neuroendocrinol, 2016. 28(10).
  34. Bjork Wilhelms, D., E. Mirrasekhian, J. Zajdel, A. Kumar Singh and D. Engblom, . PLoS One, 2016. 11(11): p. e0166153.
  35. Wilhelms, D.B., M. Kirilov, E. Mirrasekhian, A. Eskilsson, U.O. Kugelberg, C. Klar, D.A. Ridder, H.R. Herschman, M. Schwaninger, A. Blomqvist and D. Engblom, . J Neurosci, 2014. 34(35): p. 11684-90.
  36. Ruud, J., D.B. Wilhelms, A. Nilsson, A. Eskilsson, Y.J. Tang, P. Strohle, R. Caesar, M. Schwaninger, T. Wunderlich, F. Backhed, D. Engblom and A. Blomqvist, . FASEB J, 2013. 27(5): p. 1973-80.
  37. Engstrom Ruud, L., D.B. Wilhelms, A. Eskilsson, A.M. Vasilache, L. Elander, D. Engblom and A. Blomqvist, . Neuropharmacology, 2013. 71: p. 124-9.

Latest publications from LiU DiVA

2026

Samia Munir Ehrlington, Jens Wretborn, Daniel Wilhelms (2026) Academic Emergency Medicine, Vol. 33 (Article in journal)
Samia Munir Ehrlington, Jens Wretborn, Daniel Wilhelms (2026) Academic Emergency Medicine, Vol. 33, Article e70266 (Article in journal)
Erika Hörlin, David Ekermo, Daniel Wilhelms, Ann Catrine Eldh (2026) BMC Geriatrics, Vol. 26, Article 144 (Article in journal)

Research group

Organisation