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Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA, shows a new study. The results may also explain why combining certain cancer drugs can produce the opposite of the intended effect.

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired by the cell - a mistake with potentially catastrophic outcomes.

Tumour cells in colorectal cancer exploit an important signalling pathway that normally controls embryo development. Researchers have now shown how a protein that controls limb development make colorectal cancer cells more likely to spread.

Fourteen researchers at LiU have received grants totalling more than SEK 64 million. This is the result when the Swedish Research Council has awarded nearly SEK 1.1 billion in research grants for the medical and health sciences.