福利姬

We study the molecular mechanisms that preserve genome stability in mammalian cells and their roles in cancer and ageing.

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA, shows a new study. The results may also explain why combining certain cancer drugs can produce the opposite of the intended effect.

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired by the cell - a mistake with potentially catastrophic outcomes.