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Antonios Pantazis

Senior Associate Professor

Capturing the molecular transitions governing cellular electrical excitability.

Ion channel biophysics

Understanding the basis of cellular excitability in health and disease.

Our bodies are 鈥渨et computers鈥�, utilizing electrical signals to mediate nerve function, a regular heart rhythm, muscle contraction and other physiological functions. Voltage-gated ion channels are fascinating macromolecules that span the cell membrane and, upon receipt of an electrical signal, allow specific ions to cross into or out of the cell. By controlling ionic conduction, ion channels govern cellular excitability; that is, the ability of a cell to generate, and respond to, electrical signals.

My group combines innovative electrophysiological, optical and computational approaches to investigate how the intricate molecular architecture of ion channels relates to their function and regulation; and how ion channel function or dysfunction governs cellular excitability in health and disease.

Latest publications

2026

Mario Nappi, Damon Frampton, Ali Kusay, Kaiqian Wang, Sümeyye Süheda Yasarbas, Serena Pozzi, Francesco Miceli, Sara I. Liin, Maurizio Taglialatela, Antonios Pantazis (2026) Nature Communications, Vol. 17, Article 2381 (Article in journal)

2025

Marina Angelini, Nicoletta Savalli, Federica Steccanella, Savana Maxfield, Serena Pozzi, Marino DiFranco, Stephen C. Cannon, Antonios Pantazis, Riccardo Olcese (2025) Nature Communications, Vol. 16, Article 4847 (Article in journal)
Kaiqian Wang, Michelle Nilsson, Marina Angelini, Riccardo Olcese, Fredrik Elinder, Antonios Pantazis (2025) Nature Communications, Vol. 16, Article 3815 (Article in journal)
Pia Dahlberg, Serena Pozzi, Linda Bulmer, Alessia Golluscio, Michelle Nilsson, Anders Nygren, Peter Larsson, Antonios Pantazis, Anders Gummesson (2025) Journal of Molecular and Cellular Cardiology, Vol. 203, p. 47-58 (Article in journal)

2024

Antonios Pantazis, William J. Brackenbury (2024) BIOELECTRICITY, Vol. 6, p. 288-291 (Article in journal)
Michelle Nilsson, Kaiqian Wang, Teresa Mínguez-Viñas, Marina Angelini, Stina Berglund, Riccardo Olcese, Antonios Pantazis (2024) Science Advances, Vol. 10, Article eadp6665 (Article in journal)

2023

Teresa Mínguez鈥怴iñas, Varsha Prakash, Kaiqian Wang, Sarah Lindström, Serena Pozzi, Stuart A. Scott, Elizabeth Spiteri, David A. Stevenson, Euan A. Ashley, Cecilia Gunnarsson, Antonios Pantazis (2023) Journal of Physiology, Vol. 601, p. 5367-5389 (Article in journal)

2022

Michelle Nilsson, Sarah H Lindström, Maki Kaneko, Kaiqian Wang, Teresa Minguez-Viñas, Marina Angelini, Federica Steccanella, Deborah Holder, Michela Ottolia, Riccardo Olcese, Antonios Pantazis (2022) Proceedings of the National Academy of Sciences of the United States of America, Vol. 119 (Article in journal)

CV

Positions and Education

  • 2025
    Senior Associate Professor, Link枚ping University
  • 2023
    Swedish Fernstr枚m Prize
  • 2021 - 2025
    Associate Professor, Link枚ping University
  • 2018 - 2021
    Assistant Professor, Link枚ping University
  • 2012 - 2018
    Assistant Researcher, University of California at Los Angeles, Dept. of Anesthesiology
  • 2008 - 2012
    Postdoc, University of California at Los Angeles, Dept. of Anesthesiology
  • 2006 - 2008
    Postdoc, University College London, Dept. of Pharmacology
  • 2002-2006
    PhD, Cambridge University (Churchill College)
  • 1999-2002
    BA in Natural Sciences, Cambridge University (Churchill College)

News

Two researchers in a lab discuss a graph on a computer screen.

How molecules can 鈥榬emember鈥� and contribute to memory

Researchers have discovered how an ion channel in the brain鈥檚 neurons has a kind of 鈥榤olecular memory鈥�, which contributes to the formation and preservation of lifelong memories.
Kaiqian Wang.

Discovery about pain signalling may contribute to better treatment

LiU researchers have pinpointed the exact location of a specific protein fine-tuning the strength of pain signals. The knowledge can be used to develop drugs for chronic pain that are more effective and have fewer side effects.
Researcher Antonios Pantazis sits in his office and shows his 3D model of ion channels in different colors.

Antonios Pantazis channels his passion for ion channels

Antonios Pantazis has recently been awarded the prestigious Swedish Fernström Prize for his work on ion channels. His lab aims to unravel the molecular mechanisms of ion channels and their role in various diseases, such as epilepsy and arrhythmias.

Organisation

The Division of Cell and Neurobiology (CNB)

The Division of Cell and Neurobiology is a dynamic and innovative environment where we conduct research and teaching on both the structure and function of various cells as well as the nervous system and sensory organs.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.
Image of molecules that will take you to WCMM's homepage.

Wallenberg Centre for Molecular Medicine at LiU

WCMM at LiU focuses on the medicine-technology interface, and build upon our existing strengths in research within medical technology, materials science and bioengineering.

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