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Photo of Linnea Björk

Linnea Björk

Postdoc

My research focuses on the synthesis of conjugated organic molecules with tunable optical properties, particularly thiophene-based molecules. I study how small structural modifications, such as changes in heterocycles, side chains, or stereochemistry, influence fluorescence, chiroptical response, supramolecular organization, and interactions with biological targets.

The molecules are mainly used as fluorescent ligands for studying protein aggregates associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, enabling optical discrimination between different aggregate structures.

My work lies at the interface of medicinal chemistry and materials science, with a focus on functional molecules for studying complex biological systems.

Publications

2025

Linnea Björk (2025) (Doctoral thesis, comprehensive summary)
Takahiro Watanabe, Priyanka Swaminathan, Linnea Björk, Ayaka Nakanishi, Hisako Sato, Tamotsu Zako, Peter Nilsson, Mikael Lindgren (2025) ChemPhotoChem, Vol. 9, Article e202400225 (Article in journal)

2024

Linnea Björk, Robert Selegård, Marcus Bäck, Per Hammarström, Mikael Lindgren, Peter Nilsson (2024) ChemPhotoChem, Vol. 8, Article e202300183 (Article in journal)

2023

Linnea Björk, Therése Klingstedt, Peter Nilsson (2023) ChemBioChem, Vol. 24, Article e202300044 (Article, review/survey)
Linnea Björk, Hamid Shirani, Yogesh Todarwal, Mathieu Linares, Ruben Vidal, Bernardino Ghetti, Patrick Norman, Therése Klingstedt, K. Peter R. Nilsson (2023) European Journal of Organic Chemistry, Vol. 26, Article e202300583 (Article in journal)