Extracellular vesicles opsonized by monomeric C-reactive protein (CRP) are accessible as autoantigens in patients with systemic lupus erythematosus and associate with autoantibodies against CRP
Karlsson J, Wetterö J, Potempa LA, Fernandez-Botran R, O'Neill Y, Wirestam L, Mobarrez F and Sjöwall C.
Journal of Autoimmunity, 2023-09-01, Volume 139, Article 103073,
Conformational state of C-reactive protein is critical for reducing immune complex-triggered type I interferon response: Implications for pathogenic mechanisms in autoimmune diseases imprinted by type I interferon gene dysregulation
Svanberg C, Enocsson H, Govender M, Martinsson K, Potempa LA, Rajab IM, Fernandez-Botran R, Wetterö J, Larsson M och Sjöwall C.
C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205
Enocsson H, Gullstrand B, Eloranta M-L, Wetterö J, Leonard D, Rönnblom L, Bengtsson A och Sjöwall C.
Front. Immunol., 28 January 2021 |
Figur 2 CRP-nivåer bland patienter med och utan detekterbara IL-6-nivåer (Z-axel) tillsammans med olika CRP-genotyp (rs1205) och typ I IFN-gensignatur (IGS) status (X-axel). Staplar visar medianvärden.
